Error in exim main log for VPS

Error in exim main log for VPS:
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2013-04-11 00:38:57 H=localhost ([xx.xx.xx.xx]) [127.0.0.1] Warning: Sender rate 1.0 / 1h
2013-04-11 00:38:57 1O0rkv-0004ff-M9 <= test@domain.com H=localhost ([xx.xx.xx.xx]) [127.0.0.1] P=esmtpa

A=fixed_login:test@domain.com S=987 id=01087a747067959825bcc6fd91dfbfa9.squirrel@xx.xx.xx.xx
2013-04-11 00:39:01 1O0rkv-0004ff-M9 gmail-smtp-in.l.google.com [xx.xx.xx.xx] Connection refused
2013-04-11 00:39:04 1O0rkv-0004ff-M9 alt1.gmail-smtp-in.l.google.com [xx.xx.xx.xx] Connection refused
2013-04-11 00:39:07 1O0rkv-0004ff-M9 alt4.gmail-smtp-in.l.google.com [xx.xx.xx.xx] Connection refused
2013-04-11 00:39:07 1O0rkv-0004ff-M9 == domain@gmail.com R=lookuphost T=remote_smtp defer (111):

Connection refused

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Chain OUTPUT (policy ACCEPT)
target     prot opt source               destination
ACCEPT     tcp  —  anywhere             localhost           tcp dpt:smtp
REJECT     tcp  —  anywhere             anywhere            tcp dpt:smtp reject-with icmp-port-unreachable
acctboth   all  —  anywhere             anywhere
====================

FIX:

root@server [~]# iptables -D OUTPUT 2
root@server [~]# iptables -D OUTPUT 1

root@server [~]# /etc/init.d/iptables save
root@server [~]# /etc/init.d/iptables restart
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Error in exim main log for VPS, Hostripples Web Hosting
HR-ADMIN